Publications

2021

Ren E, Kim S, Mohamad S, Huguet SF, Shi Y, Cohen AR, Piddini E, Carazo Salas RE. Deep learning-enhanced morphological profiling predicts cell fate dynamics in real-time in hPSCs. bioRxiv. 2021 Aug 01. doi: https://doi.org/10.1101/2021.01.30.428961.

Kim S, Ren E, Marco Casanova P, Piddini E, Carazo Salas RE. Multiplexed live visualization of cell fate dynamics in hPSCs at single-cell resolution. bioRxiv. 2021 Jan 31. doi: https://doi.org/10.1101/2021.01.30.428961.

2019

Chessel A, Carazo Salas RE. From observing to predicting single-cell structure and function with high-throughput/high-content microscopy. Essays Biochem. 2019 Jul 3;63(2):197-208. doi: 10.1042/EBC20180044.

2018

Activation of polarized cell growth by inhibition of cell polarity. Geymonat M, Chessel A, Dodgson J, Punter H, Horns F, Csikász Nagy A, Carazo Salas RE#. BioRxiv 2018 Aug. doi: https://doi.org/10.1101/402990.

2017

Osokin A, Chessel A, Carazo Salas RE, Vaggi F. GANs for Biological Image Synthesis. arXiv 2017 and ICCV 2017. arXiv:1708.04692.

Williams E, Moore J, Li S, Rustici G, Tarkowska A, Chessel A, Leo S, Antal B, Ferguson RK, Sarkans U, Brazma A, Carazo Salas RE, Swedlow JR. The Image Data Resource: A Scalable Platform for Biological Image Data Access, Integration, and Dissemination. Nature Methods 2017 and BioRxiv 2016. Resource available at https://idr.openmicroscopy.org/.

Del Sol A, Thiesen HJ, Imitola J, Carazo Salas RE. Big-Data-Driven Stem Cell Science and Tissue Engineering: Vision and Unique Opportunities. Cell Stem Cell. 2017 Feb 2;20(2):157-160.

Lechler T, Carazo Salas RE. Editorial overview: Cell architecture: Mechanisms and scales of cellular organization and decision making. Curr Opin Cell Biol. 2017 Feb;44:iv-v. doi: 10.1016/j.ceb.2017.03.009. Issue Co-Editor.

Dodgson J, Chessel A, Vaggi F, Giordan M, Yamamoto M, Arai K, Madrid M, Geymonat M, Abenza JF, Cansado J, Sato M, Csikasz-Nagy A, Carazo Salas RE. Reconstructing regulatory pathways by systematically mapping protein localization interdependency networks. BioRxiv. 2017 Mar.

2016

Wagstaff L, Goschorska M, Kozyrska K, Duclos G, Kucinski I, Chessel A, Hampton-O’Neil L, Bradshaw CR, Allen GE, Rawlins EL, Silberzan P, Carazo Salas RE and Piddini E. Mechanical cell competition kills cells via induction of lethal p53 levels. Nature Comm. 2016, 7, 11373.

Xi W, Schmidt CK, Sanchez S, Gracias DH, Carazo Salas RE, Butler R, Lawrence N, Jackson SP, Schmidt OG. Molecular Insights into Division of Single Human Cancer Cells in On-Chip Transparent Microtubes. ACS Nano. 2016 Jun 28;10(6):5835-46. doi: 10.1021/acsnano.6b00461. Epub 2016 Jun 15.

2015

Antal B, Chessel A, Carazo Salas RE. Mineotaur: a tool for high-content microscopy screen sharing and visual analytics. Genome Biology. 2015 Dec 17;16(1):283.

Abenza JF, Couturier E, Dodgson J, Dickmann J, Chessel A, Dumais J, Carazo Salas RE. Wall mechanics and exocytosis define the shape of growth domains in fission yeast. Nature Communications. 2015 Oct 12;6:8400.

Jeffares DC, Rallis C, Rieux A, Speed D, Převorovský M, Mourier T, Marsellach FX, Iqbal Z, Lau W, Cheng TM, Pracana R, Mülleder M, Lawson JL, Chessel A, Bala S, Hellenthal G, O’Fallon B, Keane T, Simpson JT, Bischof L, Tomiczek B, Bitton DA, Sideri T, Codlin S, Hellberg JE, van Trigt L, Jeffery L, Li JJ, Atkinson S, Thodberg M, Febrer M, McLay K, Drou N, Brown W, Hayles J, Carazo Salas RE, Ralser M, Maniatis N, Balding DJ, Balloux F, Durbin R, Bähler J. The genomic and phenotypic diversity of Schizosaccharomyces pombe. Nature Genetics. 2015 Mar;47(3):235-41.

Kakui Y, Sunaga T, Arai K, Dodgson J, Ji L, Csikász-Nagy A, Carazo Salas R, Sato M. Module-based construction of plasmids for chromosomal integration of the fission yeast Schizosaccharomyces pombe. Open Biol. 2015 Jun;5(6):150054. doi: 10.1098/rsob.150054.

2014

Graml V, Studera X, Lawson JL, Chessel A, Geymonat M, Bortfeld-Miller M, Walter T, Wagstaff L, Piddini E, Carazo Salas RE. A genomic Multiprocess survey of the machineries that control and link cell shape, microtubule organisation and cell-cycle progression. Developmental Cell. 2014 Oct 27;31(2):227-39. Journal Cover. Interview in The Naked Scientist.

Vaggi F, Schiavinotto T, Lawson JL, Chessel A, Dodgson J, Geymonat M, Sato M, Carazo Salas RE, Csikász-Nagy A. A network approach to mixing delegates at meetings. eLife. 2014;3:e02273.

Abenza JF, Chessel A, Raynaud WG, Carazo Salas RE. Dynamics of cell shape inheritance in fission yeast. PLoS One. 2014 Sep 11;9(9):e106959. doi: 10.1371/journal.pone.0106959. eCollection 2014.

Xi W, Schmidt CK, Sanchez S, Gracias DH, Carazo Salas RE, Jackson SP, Schmidt OG. Rolled-up functionalized nanomembranes as three-dimensional cavities for single cell studies. Nano Lett. 2014 Aug 13;14(8):4197-204. doi: 10.1021/nl4042565. Epub 2014 Mar 10.

2013

Lawson JL, Carazo Salas RE. Microtubules: greater than the sum of the parts. Biochem Soc Trans. 2013 Dec;41(6):1736-44. doi: 10.1042/BST20130239.

Csikász-Nagy A, Sato M, Carazo Salas RE. Projecting cell polarity into the next decade. Philos Trans R Soc Lond B Biol Sci. 2013 Sep 23;368(1629):20130001. doi: 10.1098/rstb.2013.0001. Issue Co-Editor.

Bajpai A, Feoktistova A, Chen JS, McCollum D, Sato M, Carazo Salas RE, Gould KL, Csikász-Nagy A. Dynamics of SIN asymmetry establishment. PLoS Comput Biol. 2013;9(7):e1003147. doi: 10.1371/journal.pcbi.1003147.

Dodgson J, Chessel A, Yamamoto M, Vaggi F, Cox S, Rosten E, Albrecht D, Geymonat M, Csikasz-Nagy A, Sato M, Carazo Salas RE. Spatial segregation of polarity factors into distinct cortical clusters is required for cell polarity control. Nat Commun. 2013;4:1834. doi: 10.1038/ncomms2813.

 

2012

Vaggi F, Dodgson J, Bajpai A, Chessel A, Jordán F, Sato M, Carazo Salas RE, Csikász-Nagy A. Linkers of cell polarity and cell cycle regulation in the fission yeast protein interaction network. PLoS Comput Biol. 2012;8(10):e1002732. doi: 10.1371/journal.pcbi.1002732.

2007

Carazo Salas R, Nurse P. Sorting out interphase microtubules. Mol Syst Biol. 2007;3:95. doi: 10.1038/msb4100136. Epub 2007 Mar 27.

Salinas S, Carazo Salas RE, Proukakis C, Schiavo G, Warner TT. Spastin and microtubules: Functions in health and disease. J Neurosci Res. 2007 Sep;85(12):2778-82. doi: 10.1002/jnr.21238.

2006

Carazo Salas RE, Nurse P. Self-organization of interphase microtubule arrays in fission yeast. Nat Cell Biol. 2006 Oct;8(10):1102-7. doi: 10.1038/ncb1479.

2005

Salinas S, Carazo Salas RE, Proukakis C, Cooper JM, Weston AE, Schiavo G, Warner TT. Human spastin has multiple microtubule-related functions. J Neurochem. 2005 Dec;95(5):1411-20. doi: 10.1111/j.1471-4159.2005.03472.x.

Carazo Salas RE, Antony C, Nurse P. The kinesin Klp2 mediates polarization of interphase microtubules in fission yeast. Science. 2005 Jul 8;309(5732):297-300. doi: 10.1126/science.1113465.

2003

Carazo Salas RE, Karsenti E. Long-range communication between chromatin and microtubules in Xenopus egg extracts. Curr Biol. 2003 Sep 30;13(19):1728-33. doi: 10.1016/j.cub.2003.09.006.

Schatz CA, Santarella R, Hoenger A, Karsenti E, Mattaj IW, Gruss OJ, Carazo Salas RE. Importin alpha-regulated nucleation of microtubules by TPX2. EMBO J. 2003 May 1;22(9):2060-70. doi: 10.1093/emboj/cdg195.

2001

Carazo Salas RE, Gruss OJ, Mattaj IW, Karsenti E. Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly. Nat Cell Biol. 2001 Mar;3(3):228-34. doi: 10.1038/35060009.

Gruss OJ, Carazo Salas RE, Schatz CA, Guarguaglini G, Kast J, Wilm M, Le Bot N, Vernos I, Karsenti E, Mattaj IW. Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell. 2001 Jan 12;104(1):83-93. doi: 10.1016/s0092-8674(01)00193-3.

 

1999

Carazo Salas RE, Guarguaglini G, Gruss OJ, Segref A, Karsenti E, Mattaj IW. Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature. 1999 Jul 8;400(6740):178-81. doi: 10.1038/22133.